Bioassay of the Protein Relaxin

SUMMARY:

The Relaxin data frame has 198 rows and 3 columns giving the results of 9 runs of a bioassay of the protein relaxin.

DATA DESCRIPTION:

This data frame contains the following columns:

VALUE:

Run
a factor giving the run number.
conc
known concentration of the relaxin protein (ng/ml).
cAMP
amount of intracellular adenosine-3 ,5-cyclic monophosphate (cAMP) released (pmole/ml).

SOURCE:

These data were given in Fei, Gross, Lofgren, Mora-Worms, and Chen (1990), "Cyclic AMP response to recombinant human relaxin by cultured endometrial cells - a specific and high througput in-vitro bioassay", Biochemical and Biophysical Research Communications, vol. 170, pp 214-222. They are described in section 1.1.4 of Davidian and Giltinan (1995), "Nonlinear Models for Repeated Measurement Data", Chapman and Hall, London and analyzed in section 10.4.2 of the same book.

SEE ALSO:

, , , .

EXAMPLES:

Relaxin.lis <- nlsList(cAMP ~ fpl(conc, A, B, ld50, scal), 
                       data = Relaxin, cluster = ~ Run) 
Relaxin.nlme <- nlme(Relaxin.lis)