The
Relaxin
data frame has 198 rows and 3 columns giving the results
of 9 runs of a bioassay of the protein relaxin.
This data frame contains the following columns:
,5
-cyclic monophosphate (cAMP)
released (pmole/ml).
These data were given in Fei, Gross, Lofgren, Mora-Worms, and Chen (1990), "Cyclic AMP response to recombinant human relaxin by cultured endometrial cells - a specific and high througput in-vitro bioassay", Biochemical and Biophysical Research Communications, vol. 170, pp 214-222. They are described in section 1.1.4 of Davidian and Giltinan (1995), "Nonlinear Models for Repeated Measurement Data", Chapman and Hall, London and analyzed in section 10.4.2 of the same book.
Relaxin.lis <- nlsList(cAMP ~ fpl(conc, A, B, ld50, scal), data = Relaxin, cluster = ~ Run) Relaxin.nlme <- nlme(Relaxin.lis)